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  宋宝兴  比较基因组及数量遗传学实验室主任


   Emailbaoxing.song@pku-iaas.edu.cn

   研究方向:基因组进化、植物的环境适应性、群体遗传学、数量遗传学





个人简介:

2022-至今 北京大学现代农业研究院                    研究员

2018-2022 美国康奈尔大学                                博士后

2014-2018 德国马克斯·普朗克植物育种研究所    博士

2010-2013 西北农林科技大学                             硕士

2006-2010 郑州大学                                          学士

    

主要职:

Frontiers in Plant Science Review Editor

iMate期刊青年编委

Beverage Plant Research Early Career Editor

中国生物工程学会计算生物学与生物信息专业委员会委员

青岛大学计算机科学技术学院兼职研究生导师

 

研究域:

        本课题组致力于通过农作物和近源物种的遗传研究,实现高效、环境友好、并可持续的农业发展模式。通过开发并应用最前沿的分子进化和群体遗传学理论,分析农业领域在组学时代产生的海量数据,长期进化和人工选育过程中的关键农业性状和环境适应性的主效基因及分子机制并应用于分子设计育种。

       1)农作物和近源野生物种的跨物种和群体比较基因组学:结合不断更新的基因组测序技术,开发新的算法和软件深度挖掘基因组数据,解析作物优良性状的遗传与调控机制。

       2)趋同进化的遗传机理:通过分析多种农作物和近源野生物种农艺性状进化和适应环境胁迫等理解植物进化的分子机理,为农作物育种寻找候选基因型。

       3)比较遗传学和发育组学:解析不同基因型如何影响不同物种器官的建成和发育的进化和分子机理。

 

      实验室代码托管请见:


 http://github.com/baoxingsong/

 

研究组致力于培养善于独立思考、勇于探索、具有领导力的青年科学家。研究组欢迎理想远大,聪明勤奋、品格坚韧、能够自我管理的学生、青年学者和业界人士咨询、加盟!





 代表性文:#equal contribution; *corresponding

     

   1. Baoxing Song*, Santiago Marco-Sola, Miquel Moreto, Lynn Johnson, Edward S. Buckler*, Michelle C. Stitzer*. AnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication. PNAS. 2022

   2. Baoxing Song*, Edward S. Buckler, Hai Wang, Yaoyao Wu, Evan Rees, Elizabeth A. Kellogg, Daniel J. Gates, Merritt Khaipho-Burch, Peter J. Bradbury, Jeffrey Ross-Ibarra, Matthew B. Hufford and M. Cinta Romay*. Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize. Geneme Research. 2021

   3. Baoxing Song, Richard Mott, Xiangchao Gan*. Recovery of novel association loci in Arabidopsis thaliana and Drosophila melanogaster through leveraging INDELs association and integrated burden test. PLoS Genetics. 2018

   4. Baoxing Song*#, Qing Sang#, Hai Wang, Huimin Pei, XiangChao Gan* and Fen Wang*. Complement Genome Annotation Lift Over Using a Weighted Sequence Alignment Strategy. Frontiers in Genetics. 2019

   5. Fen Wang*#, Baohui Zhang#, Di Wen#, Rong Liu, Xinzhuan Yao, Zhi Chen, Ren Mu, Huimin Pei, Min Liu, Baoxing Song* and Litang Lu*. Chromosome-scale genome assembly of Camellia sinensis combined with multi-omics provides insights into its responses to infestation with green leafhoppers. 2022

   6. Fen Wang , Zhi Chen, Huimin Pei, Zhiyou Guo, Di Wen, Rong Liu, Baoxing Song*. Transcriptome profiling analysis of tea plant (Camellia sinensis) using Oxford Nanopore long-read RNA-Seq technology. Gene. 2021

   7. Fen Wang#, Baoxing Song#, Xing Zhao, Yaotian Miao, Dengyun Li, Na Zhou, Pengfei Jiang, Qing Sang, Jingfei Huang, Deli Zhang*. Prediction and analysis of the protein-protein interaction networks for chickens, cattle, dogs, horses and rabbits. Current bioinformatics. 2016

   8. Baoxing Song#, Fen Wang#, Yang Guo, Qing Sang, Min Liu, Dengyun Li, Wei Fang, Deli Zhang. Protein–protein interaction network‐based detection of functionally similar proteins within species. Proteins: Structure, Function, and Bioinformatics. 2012

   9. Baoxing Song, Xiaoquan Su, Jian Xu, Kang Ning*. MetaSee: an interactive and extendable visualization toolbox for metagenomic sample analysis and comparison. PLoS One. 2012