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罗晓  大豆分子生物学与分子设计育种实验室主任


邮箱:xiao.luo@pku-iaas.edu.cn

研究方向:(1)光周期调控大豆开花时间的基因网络解析;

                  (2)大豆耐逆功能基因发掘及利用。


个人简介:

       2008年09月-2012年06月:东北农业大学生命科学学院,Ph.D.(博士学位);

       2012年07月-2013年12月:中科院东北地理与农业生态研究所,大豆分子设计育种重点实验室,助理研究员;

       2014年01月-2016年07月:中科院上海植物逆境生物学研究中心,博士后;新加坡国立大学访问学者(2014年01月-2014年05月);

       2016年08月-2018年11月:中科院上海植物逆境生物学研究中心,助理研究员;

       2018年12月-2020年10月:中科院上海植物逆境生物学研究中心,副研究员;

       2020年11月-至今:北京大学现代农业研究院,研究员、独立课题组长(Principal Investigator /PI) 

 

主要研究领域:

       大豆是世界重要的粮油兼用作物,国内大豆供需矛盾日益突出,我国大豆进口依存度持续增加,已经严重影响我国粮食安全,特别是在有限耕地的基本国情下,实现我国“大豆复兴”,是刻不容缓的国家重大战略需求。大豆是敏感型高温短日作物,光周期调控大豆开花时间不仅影响其地域适应性,而且影响产量,因此掌握光周期诱导大豆成花的分子调控机理对培育高产大豆具有重要的指导意义。此外,大豆生长和发育过程中易受到逆境(盐碱、干旱、高低温等)胁迫,因此发掘并利用耐逆关键基因对培育耐逆大豆新品种至关重要。

       本课题组将综合运用分子遗传学、基因组学、细胞生物学和生物化学等手段,在已有基础上,对大豆进行染色质修饰相关突变体的创建和收集,从染色质修饰调控的角度揭示外界环境因素(光周期及逆境等)对大豆生长发育的调控,并深入探索外界环境因素与大豆互作的分子机制和遗传网络,为大豆分子设计育种提供理论基础。主要研究方向如下:

      (1)光周期调控大豆开花时间的基因网络解析;

      (2)大豆耐逆功能基因发掘及作用机制研究。
 

发表论文:

*通讯作者;#共同第一作者

1.      Fei Huang #, Xiao Luo#, Yang Ou#, & Zhaoxu Gao#, Qiming Tang, Zhenzhen Chu, Xinguang Zhu, Yuehui He*.2023. Control of histone demethylation by nuclear-localized α-ketoglutarate dehydrogenase. Science. 381. eadf8822. 10.1126/science.adf8822.

2.      Zhicheng Zhang#, Xiao Luo#,Yupeng Yang, Yuehui He*.2023. Cold induction of nuclear FRIGIDA condensation in Arabidopsis.Nature 619, E27–E32. https://doi.org/10.1038/s41586-023-06189-z

3.      Xiao Luo#, Yang Ou#, Renjie Li#& Yuehui He*.2020.Maternal transmission of the parental ‘memory of winter cold’ in Arabidopsis. Nature Plants , 610:1211-1218.

4.      Zicong Li#, Xiao Luo#, Yang Ou#, Huijun Jiao, Li Peng, Xing Fu, Alberto P Macho, Renyi Liu&Yuehui He*.2021.JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in  Arabidopsis. Molecular Plant,14(5):732-747.

5.      Xiao Luo#, Tao Chen#, Xiaolin Zeng, Dingwei He &Yuehui He*.2019. Feedback regulation of FLC by FLOWERING LOCUS T (FT) and FD through a 5'FLC promoterregion in Arabidopsis. Molecular Plant, 12(3): 285~288.

6.      Zeng Tao#, Hongmiao Hu#,Xiao Luo#, Bei Jia, Jiamu Du*&Yuehui He*.2019. Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. Nature Plants, 5 (4)424–435.

7.      Wenya Yuan#,Xiao Luo, Zicong Li, Wannian Yang, Yizhong Wang, Rui Liu, Jiamu Du*& Yuehui He*.2016.  A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis.Nature Genetics, 48(12): 1527~1534.

8.      Xiao Luo#, Zheng Gao#, Yizhong Wang, Zhijuan Chen, Wenju Zhang, Jirong Huang,Hao Yu, Yuehui He*.2018. The NUCLEAR FACTOR-CONSTANS complex antagonizes Polycomb repression to de-repress FLOWERING LOCUS T expression in response to inductive long days in Arabidopsis. Plant Journal,95(1): 17~29. 

9.      Xiao Luo#, Yuehui He*.2020.Experiencing winter for spring flowering – a molecular epigenetic perspective on vernalization.Journal of Integrative Plant Biology, 62 (1): 104-117. ESI Highly Cited Paper.

10.   YingZhu#, Xiao Luo#, Xuxin Liu#, Wenjuan Wu, Xiaofeng Cui, Yuehui He*& Jirong Huang*.2020.Arabidopsis PEAPODs function with LIKE HETEROCHROMATIN PROTEIN1 to regulate lateral organ growth.Journal of Integrative Plant Biology, 62 (6): 812-831.

11.   Xiao Luo#, *, Meng nan Yin#, Yue hui He*.2022.Molecular genetic understanding of photoperiodic regulation of flowering timein Arabidopsis and Soybean.Int. J. Mol. Sci, 23, 466.

12.   Zhaohan Zhang#, Wanpeng Wang, Shahid Ali, Xiao Luo*, Linan Xie*.2022. CRISPR/Cas9-Mediated Multiple Knockouts in Abscisic Acid Receptor Genes Reduced the Sensitivity to ABA during Soybean Seed Germination. Int. J. Mol. Sci. 2022,18;23(24):16173.

13.   Myeongjune Jeon#, Goowon Jeong, Yupeng Yang, Xiao Luo, Daesong Jeong, Jinseul Kyung, Youbong Hyun, Yuehui He*, Ilha Lee*.2023. Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes. eLife,12:e84594. doi: 10.7554/eLife.84594.

14.   Hong Zhai, Zhao Wan, Shuang Jiao, Jingwen Zhou, Kun Xu, Haiyang Nan, Yingxiang Liu, Shangshang Xiong, Rong Fan, Jinlong Zhu, Wenting Jiang, Tian Pang, Xiao Luo, Hongyan Wu, Guang Yang, Xi Bai, Fanjiang Kong, Zhengjun Xia.2022. GmMDE genes bridge the maturity gene E1 and florigens in photoperiodic regulation of flowering in soybean. Plant Physiology,189(2), 1021–1036

15.   Zicong Li#, Danhua Jiang#, Xing Fu, Xiao Luo, Renyi Liu, Yuehui He*.2016. Coupling of histone methylation and RNA processing by the nuclear mRNA cap-binding complex. Nature Plants, 2(3):1-10.