周军会    草莓发育生物学与种质资源创新实验室主任

邮箱：junhui.zhou@pku-iaas.edu.cn

研究方向：草莓树莓肉质果发育起始的分子机制、草莓真菌病害致病机理及植物免疫反应、园艺作物基因编辑体系的开发优化及草莓树莓种质资源创新

个人简介：

       2008.09–2015.04，美国爱荷华州立大学 （Iowa State University），Ph.D.（博士）

       2015.05–2020.07，美国马里兰大学帕克分校(University of Maryland, College Park)，博士后

       2021.03 -，北京大学现代农业研究院，研究员, 草莓发育生物学与种质资源创新研究组 PI, 泰山学者青年专家

主要研究领域：

     草莓是世界上最重要的小浆果之一，其中我国的草莓种植面积和产量长期居世界首位。草莓具有生长周期相对较短(4-6月)、多年生、可以无性繁殖(匍匐茎)等特点，特别是近年来随着基因组注释的完善、转基因体系和基因编辑体系的开发，草莓逐渐发展成为研究果实发育机制、植物-微生物互作的一种模式物种。悬钩子属（Rubus）树莓具有丰富的野生种质资源且多为二倍体，基因组较小（300Mb），其果实富含SOD、鞣花酸和各种维生素，具有抗氧化、抗衰老、抗炎症、预防心血管疾病和美白皮肤等生理活性。课题组以森林草莓（2n）、栽培草莓（8n）和树莓（2n）为主要研究对象，结合多组学技术、分子生物学技术、细胞生物学技术和分子遗传学技术探究：(1). 草莓肉质果发育起始及蔷薇科果实作物肉质果发育多样性的遗传机制；(2). 草莓树莓果实品质调控的分子机制；(3). 草莓主要真菌病害（灰霉病、白粉病）的致病机理及分子抗病育种策略的开发；(4). Rubus资源收集及其各种发育性状特征的遗传机制；(5). 园艺作物基因编辑体系的优化及应用；以基因编辑为基础的草莓树莓分子设计育种策略开发。

    欢迎对课题组研究感兴趣的学生、青年学者加盟，共同发展！

代表性论文：

(#: Co-first author; *: Corresponding author)

Han，X., #, Xia Liang, X.#, Li, D., Song, M., Ma, Z., Li, R., Meng, H., Cai, Y., Song, B., Liu, Z., Zhou, H.* and Zhou, J.* (2025). A native visual screening reporter-assisted CRISPR/Cas9 system for high-efficient genome editing in strawberry. Molecular Horticulture, https://doi.org/10.1186/s43897-025-00151-5.

Zhang, C.#, Tang, Y.#, Tang, S.#, Chen, L., Yuan, H., Xu, Y., Zhou, Y., Zhang, S., Wang, J., Wen, H., Jiang, W., Pang, Y., Deng, X., Cao, X., Zhou, J.*, Song, X.* and Liu, Q.* (2024). An Inducible CRISPR-activation tool for accelerated plant regeneration. Plant Communications, 135， 5：100823.https://www.sciencedirect.com/science/article/pii/S25903462240 00439?via%3Dihub.

Zhou, J. #, Li, M. #, Li, Y., Xiao, Y., Luo,X., Gao, S., Ma,Z., Sadowski,N., Timp, W., Dardick, C., Callahan, A., Mount, S., Liu, Z. (2023). Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification. Plant Physiology, kiad409. https://doi.org/10.1093 /plphys/kiad409.

Ma, Z., Ma, L., Zhou, J.* (2023). Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions. Molecular Horticulture. https://molhort. biomedcentral.com/articles/10.1186/s43897-023-00049-0.

       Zhou, J., Sittmann, J., Guo, L., Xiao Y., Huang, X., Pulapaka, A., and Liu, Z. (2020). Gibberellin and auxin signaling genes RGA1 and ARF8 repress accessory fruit initiation in diploid strawberry. Plant Physiology, 185, 1059-1075.

       Zhou, J., Li, D., Wang, G., Wang F., Kunjal, M., Joldersma, D. and Liu, Z. (2019). Application and future perspective of CRISPR/Cas9 genome editing in fruit crops. Journal of Integrative Plant Biology, 62, 269-286. 

       Zhou, J., Wang, G. and Liu, Z. (2018). Efficient genome-editing of wild strawberry genes, vector development, and validation. Plant Biotechnology Journal, 16, 1868-1877. 

       Zhou, J., Peng, Z., Long, J., Sosso, D., Liu, B., Eom, J., Zhou, H., Huang, S., Cruz, C., Frommer, W., White, F. and Yang, B. (2015). Gene Targeting by the TAL Effector PthXo2 Reveals Cryptic Resistance Gene for Bacterial Blight of Rice. The Plant Journal, 82, 632-643.

       Antony, G. #, Zhou, J. #, Huang, S., Li, T., Liu, B., White, F., and Yang, B. (2010). Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3. The Plant Cell, 22, 3864-3876.

       Zhou, J., Song Y., Zhang Y. (2008). Advancement of Late Blight Resistance Genes in Potato. Biotechnology Bulletin, 5, 13-17.

       Chen, G., Xu, P., Pan, J., Li, Y., Zhou, J., Kuang, H., Lian, H. (2020). Inhibition of FvMYB10 transcriptional activity promotes color loss in strawberry fruit. Plant Science, https://doi.org/10.1016/j.plantsci.2020. 110578

       Wight, H., Zhou, J., Li, M., Hannenhalli, S., Mount, S. and Liu, Z. (2019). Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus.  (BioRxiv: https://www.biorxiv.org/content/10.1101/ 546135v2).

       Long, J., Song, C., Yan, F., Zhou, J., Zhou, H. and Yang, B. (2018) Non-TAL Effectors from Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice. Frontiers in Plant Science. 9:1857. https://doi: 10.3389/fpls.2018.01857.

       Li T., Huang S., Zhou J., Yang B. (2013). Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant, 6, 781-789.

       Song Y., Zhou, J., Zhang Y. (2007). Advancement of Tissue-specific Promoter in Plants. Biotechnology Bulletin, 6, 21-24.