周军会 草莓发育生物学与种质资源创新实验室主任
邮箱：junhui.zhou@pku-iaas.edu.cn
研究方向：草莓树莓肉质果发育起始的分子机制、草莓真菌病害致病机理及植物免疫反应、园艺作物基因编辑体系的开发优化及草莓树莓种质资源创新
个人简介：
2008.09–2015.04，美国爱荷华州立大学 （Iowa State University），Ph.D.（博士）
2015.05–2020.07，美国马里兰大学 (University of Maryland, College Park)，博士后
2021.03 -，北京大学现代农业研究院，研究员, 草莓发育生物学与种质资源创新研究组 PI, 泰山学者青年专家
主要研究领域：
草莓经济价值和营养价值极高，是世界上最重要的小浆果之一。我国的草莓种植面积和产量长期居世界首位，总产值超过1000亿元。其中，森林草莓(Fragaria vesca)以其较短的生长周期(4-6月)，高质量的T2T基因组及注释信息(2n=14)、成熟的转基因体系和基因编辑体系，逐渐发展成为研究果实发育、成熟与品质调控，植物-微生物互作的模式物种。悬钩子属（Rubus）树莓具有丰富的野生种质资源且多为二倍体，基因组较小（300Mb），其果实富含SOD、鞣花酸、树莓酮和各种维生素，具有抗氧化、抗衰老、抗炎症、预防心血管疾病和美白皮肤等生理活性。课题组以森林草莓（2×）、栽培草莓（8×）和树莓（2×）为主要研究对象，结合时空组学、分子生物学、细胞生物学和分子遗传学技术探究：(1). 草莓肉质果发育起始及蔷薇科果实作物肉质果发育多样性的遗传机制；(2). 草莓树莓果实品质调控的分子机制；(3). 草莓与主要真菌（灰霉菌、白粉菌、AM菌根）和非生物胁迫之间的互作机制； (4). Rubus资源收集及其各种发育特征性状的遗传机制解析；(5). 园艺作物基因编辑体系（CRISPR/Cas, Base editor, Prime editor）的优化及应用；以基因编辑为基础的草莓树莓分子设计育种策略开发。
欢迎对课题组研究感兴趣的学生、青年学者加盟，共同发展！
科研项目：
1）2026-2029，国家自然科学基金面上项目（32572998），MADS-Box家族转录因子FBP9调控草莓肉质果发育起始的分子机制解析，主持。
2）2023-2026，年国家自然科学基金面上项目（32272692），生长素响应因子ARF6a和ARF8协同调控草莓果实发育起始的分子机制研究，主持。
3）2025-2028，山东省重点研发计划（农业良种工程）项目（2025LZGC026），早熟硬果型草莓新品种培育及应用，技术负责人。
4）2022-2025，泰山学者青年专家人才项目，主持。
代表性论文：
(#: Co-first author; *: Corresponding author)
Li X.#, Han X.#, Liu S.#, Zhang Q.#, Guan J.#, Zheng M., Tang Y., Xu P., Bian J., Li K., Wang Z., Zhou H., Yang G., Lian H.*, He H.*, Zhou J.* (2026). Two telomere-to -telomere genome assemblies and comparisons revealed the conserved “toolkit” genes for sugar accumulation in Rubus genus. Plant Communications, in press.
Zheng M., Sun G., Han X., Sun Y., Liu S., Li X., Guan J., Zhang Q., Zhou J. (2026). Telomere-to- Telomere gap-free genome assembly of the allotetraploid wild raspberry Rubus alceifolius Poir. Scientific Data, https://www.nature.com/articles/s41597-026-07160-z.
Li S.#, Li Y.#, Huang X., Yan H., Sun F., Zhang Z., Zhu C., Ma L., Zhai W., Sun J., Zhang L., Zhou J. (2026). Development of a highly efficient and widely applicable protoplast isolation and transformation system for strawberry. Horticultural Plant Journal, in press.
Han T., Zhang Y., Tang Y., Zhao X., Wang G.*, Zhou J.*(2026). Functional analysis of FveBZR1-2 reveals a potential auxin–BR regulatory module in early receptacle elongation of strawberry. Plant Science, https://doi.org/10.1016/j.plantsci.2026.113072.
Han，X.#, Xia Liang, X.#, Li, D., Song, M., Ma, Z., Li, R., Meng, H., Cai, Y., Song, B., Liu, Z., Zhou, H.* and Zhou, J.* (2025). A native visual screening reporter-assisted CRISPR/Cas9 system for high-efficient genome editing in strawberry. Molecular Horticulture, https://doi.org/10.1186/s43897-025-00151-5.
Zhang, C.#, Tang, Y.#, Tang, S.#, Chen, L., Yuan, H., Xu, Y., Zhou, Y., Zhang, S., Wang, J., Wen, H., Jiang, W., Pang, Y., Deng, X., Cao, X., Zhou, J.*, Song, X.* and Liu, Q.* (2024). An Inducible CRISPR-activation tool for accelerated plant regeneration. Plant Communications, 135， 5：100823.https://www.sciencedirect.com/science/article/pii/S25903462240 00439?via%3Dihub.
Zhou, J. #, Li, M. #, Li, Y., Xiao, Y., Luo,X., Gao, S., Ma,Z., Sadowski,N., Timp, W., Dardick, C., Callahan, A., Mount, S., Liu, Z. (2023). Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification. Plant Physiology, kiad409. https://doi.org/10.1093 /plphys/kiad409.
Ma, Z., Ma, L., Zhou, J.* (2023). Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions. Molecular Horticulture. https://molhort. biomedcentral.com/articles/10.1186/s43897-023-00049-0.
Zhou, J., Sittmann, J., Guo, L., Xiao Y., Huang, X., Pulapaka, A., and Liu, Z. (2021). Gibberellin and auxin signaling genes RGA1 and ARF8 repress accessory fruit initiation in diploid strawberry. Plant Physiology, 185, 1059-1075.
Zhou, J., Li, D., Wang, G., Wang F., Kunjal, M., Joldersma, D. and Liu, Z. (2019). Application and future perspective of CRISPR/Cas9 genome editing in fruit crops. Journal of Integrative Plant Biology, 62, 269-286.
Zhou, J., Wang, G. and Liu, Z. (2018). Efficient genome-editing of wild strawberry genes, vector development, and validation. Plant Biotechnology Journal, 16, 1868-1877.
Zhou, J., Peng, Z., Long, J., Sosso, D., Liu, B., Eom, J., Zhou, H., Huang, S., Cruz, C., Frommer, W., White, F. and Yang, B. (2015). Gene Targeting by the TAL Effector PthXo2 Reveals Cryptic Resistance Gene for Bacterial Blight of Rice. The Plant Journal, 82, 632-643.
Antony, G. #, Zhou, J. #, Huang, S., Li, T., Liu, B., White, F., and Yang, B. (2010). Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3. The Plant Cell, 22, 3864-3876.
Zhou, J., Song Y., Zhang Y. (2008). Advancement of Late Blight Resistance Genes in Potato. Biotechnology Bulletin, 5, 13-17.
Chen, G., Xu, P., Pan, J., Li, Y., Zhou, J., Kuang, H., Lian, H. (2020). Inhibition of FvMYB10 transcriptional activity promotes color loss in strawberry fruit. Plant Science, https://doi.org/10.1016/j.plantsci.2020. 110578
Long, J., Song, C., Yan, F., Zhou, J., Zhou, H. and Yang, B. (2018) Non-TAL Effectors from Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice. Frontiers in Plant Science. 9:1857. https://doi: 10.3389/fpls.2018.01857.
Li T., Huang S., Zhou J., Yang B. (2013). Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant, 6, 781-789.
Song Y., Zhou, J., Zhang Y. (2007). Advancement of Tissue-specific Promoter in Plants. Biotechnology Bulletin, 6, 21-24.